Monday Night Football Betting Line – 49ers @ Cardinals

The 49ers vs. Cardinals betting line for this critical Monday Night matchup has Arizona as a +7 home underdog, some sportsbooks were moving to +8.

The home team has won the last three in this series and four of the last five.  San Francisco has won five of the last six, however, Arizona beat the 49ers by 2 points late last season.

As a favorite of between 3.5 and 9.5 over the past three seasons, San Francisco has gone 13-3 Straight Up and 11-5 Against The Spread.

Arizona has won only once in 7 Monday Night Football appearances.  The 49ers are 20-6 ATS in their last 26 Monday games.

In October games, Arizona is just 1-10 Straight Up.

Following two or more consecutive losses, the Cardinals are just 2-10 Straight Up and 4-8 ATS.

Here are some more important 49ers vs. Cardinals betting trends for your consideration.

The 49ers are 15-5-3 ATS in their last 23 games following a ATS loss.

The 49ers are 13-6-1 ATS in their last 20 games following a S.U. win.

The 49ers are 13-6-1 ATS in their last 20 vs. NFC.

The 49ers are 5-0-1 ATS in their last 6 games after accumulating less than 150 yards passing in their previous game.

The Cardinals are 6-1-1 ATS in their last 8 vs. NFC.

The Cardinals are 5-1-1 ATS in their last 7 games following a S.U. loss.

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